Spectra offers the following nucleic acid products in a pure and lyophilized form as an acetate salt. All preparations are vigorously tested following preparation and purification. These are purified to >95% chemical purity by HPLC.

• Ribonucleoside 5’-monophosphates
• 2’-Deoxyribonucleotide Phosphoramidites for chemical synthesis of oligonucleotides
• Ribonucleoside 5’-triphosphates for enzymatic synthesis of RNA
• Deoxyribonucleoside 5’-triphosphates for enzymatic synthesis of DNA
• Deoxyribo/Ribonucleosides
  

		Figure 1 Purity of Deoxyribonucleoside 5’-triphosphates as assessed by high performance liquid chromatography. All four nucleotides are well separated and no significant other entities are detected. The trace represents absorbance at 254 nm and the sequence of nucleotides eluting is C, A, T, G.
		Figure 2 Enzymatic synthesis of double-stranded DNA by PCR. PCR was performed on a template contained in vector pGem-T easy. Primers were chosen to yield an amplicon of 700 bp. For each lane, three unlabeled commercially available nucleotides were mixed with a single labeled nucleotide and the latter is indicated above each lane. Amplicons (see arrow) of virtually identical intensity were obtained for every nucleotide indicating that all four reactions proceeded with uniform efficiency
		Figure 3 Enzymatic synthesis of RNA by in-vitro transcription. Reactions were performed on a template contained in vector pGem using T7 polymerase. The template yielded a transcript of 346 bp. For each lane, three unlabeled commercially available ribonucleotides were mixed with a single labeled ribonucleotide and the latter is indicated above each lane. Transcripts (see arrow) of virtually identical intensity were obtained for every nucleotide indicating that all four reactions proceeded with uniform efficiency.